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Keywords: Complications; Hepatocellular carcinoma; Laparoscopic microwave ablation; Microwave ablation; Percutaneous microwave ablation; Thermal ablation.

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In this review we provide an extensive and detailed overview of the key physical and technical aspects of MWA and of the currently available systems, and we want to discuss the most relevant published data on MWA treatments of HCC nodules in regard to clinical results and to the type and rate of complications, both in absolute terms and in comparison with RFA.

Although surgical resection is still the optimal treatment option for early-stage hepatocellular carcinoma HCC in patients with well compensated cirrhosis, thermal ablation techniques provide a valid non-surgical treatment alternative, thanks to their minimal invasiveness, excellent tolerability and safety profile, proven efficacy in local disease control, virtually unlimited repeatability and cost-effectiveness.

Among them, radiofrequency RF currents are the most used, while microwave ablations MWA are becoming increasingly popular.

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Hendriks P, Berkhout WEM, Kaanen CI, Sluijter JH, Visser IJ, van den Dobbelsteen JJ, de Geus-Oei LF, Webb AG, Burgmans MC.

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A: Ultrasound evaluation before ablation; B: Needle insertion; C: Hyperechoic boiling effect in the ablation area during the procedure; D: One month later ultrasound evaluation: The inner hyperechoic track corresponds to the position of the active probe.